Bills christen $2.1 billion Highmark Stadium in prime-time showdown with Lions

Buffalo opens its new home Thursday night against Detroit with two 1-0 teams, a resodded playing surface and one of the NFL’s most anticipated offensive matchups.

ORCHARD PARK, N.Y. (Sept. 15, 2026) — The Buffalo Bills will host the Detroit Lions Thursday night in the first regular-season game at the club’s new $2.1 billion Highmark Stadium, a gleaming facility that has already been used for two preseason games and multiple practices. The franchise has resodded the entire grass field after early signs of wear, and the venue’s vertical seating and protective canopy are designed to amplify crowd noise as the old stadium sits demolished across the street. The prime-time presentation includes a halftime performance by OneRepublic and other game-night pageantry.

Both teams enter at 1-0 after dramatic openers. Buffalo defeated Houston 36-31 when its quarterback accounted for all four touchdowns and engineered his 26th career game-winning drive to seal the victory. Detroit opened with a 31-30 overtime win over New Orleans in a game decided when the Saints failed on a two-point conversion; running back Jahmyr Gibbs and receiver Amon‑Ra St. Brown each scored twice in that contest. Kickoff is scheduled for 8:15 p.m. EDT on Amazon Prime, with Buffalo listed as a 4½-point favorite.

Attention will focus on Buffalo’s run defense and how it handles Gibbs. In Week 1 the Bills surrendered 124 yards on the ground to Houston; David Montgomery finished that game with 60 rushing yards and three touchdowns, one of them on a reception, while Gibbs produced 156 rushing yards and had five catches for 30 yards in Detroit’s opener. Buffalo enters the season with Jim Leonhard installed as defensive coordinator after a year in which the team allowed 150 or more rushing yards seven times.

The matchup also carries historical and personnel storylines. Buffalo leads the series 8-4-1 and the clubs last met on Dec. 15, 2024, in a 48-42 Bills victory that combined for 1,080 yards and 90 points. Lions coach Dan Campbell’s teams are 14-4 in prime time, including 4-0 on Thursday nights and 5-4 on the road, while Bills first-year head coach Joe Brady will look to keep Buffalo focused amid the spectacle. Stat lines to note: Buffalo’s quarterback improved his career record to 41-7 when avoiding turnovers and owns 81 rushing touchdowns — the most by any quarterback and tied for 20th on the NFL career list — and Lions defensive end Aidan Hutchinson comes off his 10th multi-sack game in 57 career appearances.

Week 1 Scoreboard

DateMatchupFinal ScoreStatus
Wed, Sep 9NE at SEA
Lumen Field
10–13Final
Thu, Sep 10SF at LAR
Melbourne Cricket Ground
27–7Final
Sun, Sep 13TB at CIN
Paycor Stadium
27–33Final
Sun, Sep 13NO at DET
Ford Field
30–31Final
Sun, Sep 13NYJ at TEN
Nissan Stadium
23–10Final
Sun, Sep 13BAL at IND
Lucas Oil Stadium
41–23Final
Sun, Sep 13ATL at PIT
Acrisure Stadium
13–20Final
Sun, Sep 13CHI at CAR
Bank of America Stadium
59–37Final
Sun, Sep 13CLE at JAX
EverBank Stadium
10–34Final
Sun, Sep 13BUF at HOU
Reliant Stadium
36–31Final
Sun, Sep 13MIA at LV
Allegiant Stadium
13–27Final
Sun, Sep 13GB at MIN
U.S. Bank Stadium
22–39Final
Sun, Sep 13WSH at PHI
Lincoln Financial Field
22–24Final
Sun, Sep 13ARI at LAC
SoFi Stadium
26–14Final
Sun, Sep 13DAL at NYG
MetLife Stadium
20–28Final
Mon, Sep 14DEN at KC
Arrowhead Stadium
10–31Final

Week 2 Schedule Sep 16-22

DateMatchupTimeStatus / TV
Thu, Sep 17DET at BUF
Highmark Stadium
8:15 PM ETScheduled
Prime Video
Sun, Sep 20CAR at ATL
Mercedes-Benz Stadium
1:00 PM ETScheduled
FOX
Sun, Sep 20MIN at CHI
Soldier Field
1:00 PM ETScheduled
FOX
Sun, Sep 20PHI at TEN
Nissan Stadium
1:00 PM ETScheduled
FOX
Sun, Sep 20PIT at NE
Gillette Stadium
1:00 PM ETScheduled
CBS
Sun, Sep 20GB at NYJ
MetLife Stadium
1:00 PM ETScheduled
FOX
Sun, Sep 20CLE at TB
Raymond James Stadium
1:00 PM ETScheduled
CBS
Sun, Sep 20NO at BAL
M&T Bank Stadium
1:00 PM ETScheduled
CBS
Sun, Sep 20CIN at HOU
Reliant Stadium
1:00 PM ETScheduled
CBS
Sun, Sep 20JAX at DEN
Empower Field at Mile High
4:05 PM ETScheduled
CBS
Sun, Sep 20LV at LAC
SoFi Stadium
4:05 PM ETScheduled
CBS
Sun, Sep 20WSH at DAL
AT&T Stadium
4:25 PM ETScheduled
FOX
Sun, Sep 20SEA at ARI
State Farm Stadium
4:25 PM ETScheduled
FOX
Sun, Sep 20MIA at SF
Levi's Stadium
4:25 PM ETScheduled
FOX
Sun, Sep 20IND at KC
Arrowhead Stadium
8:20 PM ETScheduled
NBC
Mon, Sep 21NYG at LAR
SoFi Stadium
8:15 PM ETScheduled
ESPN, ABC

NFL Standings

AFC East

TeamWLTPctDiff
BUF1001.000+5
NYJ1001.000+13
MIA010.000-14
NE010.000-3

AFC North

TeamWLTPctDiff
BAL1001.000+18
CIN1001.000+6
PIT1001.000+7
CLE010.000-24

AFC South

TeamWLTPctDiff
JAX1001.000+24
HOU010.000-5
IND010.000-18
TEN010.000-13

AFC West

TeamWLTPctDiff
KC1001.000+21
LV1001.000+14
DEN010.000-21
LAC010.000-12

NFC East

TeamWLTPctDiff
NYG1001.000+8
PHI1001.000+2
WSH010.000-2
DAL010.000-8

NFC North

TeamWLTPctDiff
MIN1001.000+17
CHI1001.000+22
DET1001.000+1
GB010.000-17

NFC South

TeamWLTPctDiff
CAR010.000-22
NO010.000-1
TB010.000-6
ATL010.000-7

NFC West

TeamWLTPctDiff
SF1001.000+20
ARI1001.000+12
SEA1001.000+3
LAR010.000-20

NFL League Leaders — 2026 Regular Season

Fantasy Football

Passing Yards Leaders
RKPlayerTeamYDS
1Tyler Shough, QBNO410
2Jordan Love, QBGB387
3Bryce Young, QBCAR361
4Josh Allen, QBBUF334
5Lamar Jackson, QBBAL324
Passing Touchdowns Leaders
RKPlayerTeamTD
1Trevor Lawrence, QBJAX4
2Kirk Cousins, QBLV3
3Carson Wentz, QBMIN3
4Jalen Hurts, QBPHI3
5Tyler Shough, QBNO3
Quarterback Rating Leaders
RKPlayerTeamRAT
1Trevor Lawrence, QBJAX151
2Jaxson Dart, QBNYG134
3Josh Allen, QBBUF131
4Lamar Jackson, QBBAL124
5Caleb Williams, QBCHI124
Rushing Yards Leaders
RKPlayerTeamYDS
1Kenneth Walker III, RBKC173
2Jahmyr Gibbs, RBDET156
3Derrick Henry, RBBAL144
4D'Andre Swift, RBCHI124
5Breece Hall, RBNYJ102
Rushing Touchdowns Leaders
RKPlayerTeamTD
1Derrick Henry, RBBAL3
2D'Andre Swift, RBCHI3
3Josh Allen, QBBUF2
4David Montgomery, RBHOU2
5Jonathan Taylor, RBIND2
Receptions Leaders
RKPlayerTeamREC
1Chris Olave, WRNO10
2Amon-Ra St. Brown, WRDET10
3Trey McBride, TEARI9
4Kalif Raymond, WRCHI8
5Kendrick Bourne, WRARI8
Receiving Yards Leaders
RKPlayerTeamYDS
1Chris Olave, WRNO182
2Zay Flowers, WRBAL150
3Christian Watson, WRGB147
4Jalen Coker, WRCAR138
5Dalton Kincaid, TEBUF130
Receiving Touchdowns Leaders
RKPlayerTeamTD
1Dallas Goedert, TEPHI2
2Christian Watson, WRGB2
3Justin Jefferson, WRMIN2
4Isaiah Likely, TENYG2
5Amon-Ra St. Brown, WRDET2
Total Touchdowns Leaders
RKPlayerTeamTTD
1Derrick Henry, RBBAL3
2David Montgomery, RBHOU3
3D'Andre Swift, RBCHI3
4Dallas Goedert, TEPHI2
5Josh Allen, QBBUF2
Total Points Leaders
RKPlayerTeamTP
1Derrick Henry, RBBAL18
2David Montgomery, RBHOU18
3D'Andre Swift, RBCHI18
4Evan McPherson, PKCIN15
5Justin Jefferson, WRMIN14